Assay Detail
Binding
CHEMBL643904
Review assay metadata, readout intent, target linkage, and publication context from the same page.
The compound was tested for the binding affinity towards Alpha-1B adrenergic receptor
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Bicyclic piperazinylbenzenesulphonamides are potent and selective 5-HT6 receptor antagonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 5 | 5.78 | 6.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL282971 | — | — | 1 | 6.00 |
| CHEMBL29433 | — | — | 1 | 5.80 |
| CHEMBL29410 | — | — | 1 | 5.70 |
| CHEMBL29846 | — | — | 1 | 5.70 |
| CHEMBL431298 | — | — | 1 | 5.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL282971 | — | Ki | = | 1000.0 | nM | 6.00 |
| CHEMBL29433 | — | Ki | = | 1584.89 | nM | 5.80 |
| CHEMBL29410 | — | Ki | = | 1995.26 | nM | 5.70 |
| CHEMBL29846 | — | Ki | = | 1995.26 | nM | 5.70 |
| CHEMBL431298 | — | Ki | = | 1995.26 | nM | 5.70 |