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Assay Detail

CHEMBL643921

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
The compound was evaluated for the alpha-2 adrenergic receptor activity in rat vas deferens.
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 4 — Cell-line / Tissue
Curated By Autocuration

Target

Adrenergic receptor alpha-2 (CHEMBL2093864)
Type PROTEIN FAMILY
Organism Rattus norvegicus

Publication

Alpha 2-adrenergic agonists/antagonists: the synthesis and structure-activity relationships of a series of indolin-2-yl and tetrahydroquinolin-2-yl imidazolines.
Hlasta DJ, Luttinger D, Perrone MH, Silbernagel MJ, Ward SJ, Haubrich DR.
J Med Chem (1987) 30 : 1555 -1562
PubMed 2887657 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.75 6.75

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL290324 1 6.75

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL290324 IC50 = 179.0 nM 6.75