Assay Detail
Binding
CHEMBL643992
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Ability to inhibit the rat muscle adenylate kinase (AK II) isozyme in competition with the ATP varied
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Adenylate kinase 2, mitochondrial (CHEMBL2376) ↗| Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
Publication
Species- or isozyme-specific enzyme inhibitors. 4. Design of a two-site inhibitor of adenylate kinase with isozyme selectivity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 1 | 6.52 | 6.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL437508 | — | — | 1 | 6.52 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL437508 | — | Ki | = | 300.0 | nM | 6.52 |