Assay Detail
Binding
CHEMBL644120
Review assay metadata, readout intent, target linkage, and publication context from the same page.
In vitro inhibition of human recombinant AChE.
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Expert |
Publication
Quaternary salts of E2020 analogues as acetylcholinesterase inhibitors for the reversal of neuromuscular block.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.52 | 7.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL245079 | HUPERZINE B | — | 1 | 7.52 |
| CHEMBL75013 | ZANAPEZIL | 2.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL245079 | HUPERZINE B | IC50 | = | 30.0 | nM | 7.52 |
| CHEMBL75013 | ZANAPEZIL | IC50 | < | 500.0 | nM | - |