Assay Detail
Binding
CHEMBL644153
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Inhibitory activity against rat adenylate kinase II was determined in the presence of ATP
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Adenylate kinase 2, mitochondrial (CHEMBL2376) ↗| Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
Publication
Species- or isozyme-specific enzyme inhibitors. 8. Synthesis of disubstituted two-substrate condensation products as inhibitors of rat adenylate kinases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 4.10 | 4.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3251358 | — | — | 1 | 4.10 |
| CHEMBL604398 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3251358 | — | Ki | = | 80000.0 | nM | 4.10 |
| CHEMBL604398 | — | Ki | = | 2200000.0 | nM | - |