Assay Detail
Binding
CHEMBL644662
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Binding affinity for human adenosine A2A receptor in CHO cells using [3H]CGS-21680
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | CHO |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
N6-substituted D-4'-thioadenosine-5'-methyluronamides: potent and selective agonists at the human A3 adenosine receptor.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 6.24 | 6.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL203357 | — | — | 1 | 6.80 |
| CHEMBL200732 | — | — | 1 | 6.65 |
| CHEMBL431733 | NAMODENOSON | 3.0 | 1 | 5.27 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL203357 | — | Ki | = | 158.0 | nM | 6.80 |
| CHEMBL200732 | — | Ki | = | 223.0 | nM | 6.65 |
| CHEMBL431733 | NAMODENOSON | Ki | = | 5360.0 | nM | 5.27 |