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Assay Detail

CHEMBL644698

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Compound was tested for its inhibitory potency against Angiotensin I converting enzyme
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Angiotensin-converting enzyme (CHEMBL1808)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Molecular and crystal structures of MDL27,467A hydrochloride and quinapril hydrochloride, two ester derivatives of potent angiotensin converting enzyme inhibitors.
Hausin RJ, Codding PW.
J Med Chem (1991) 34 : 511 -517
PubMed 1995872 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.85 6.85

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL578 ENALAPRIL 4.0 1 6.85

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL578 ENALAPRIL IC50 = 140.0 nM 6.85