Assay Detail
Binding
CHEMBL644705
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Inhibitory concentration against Angiotensin I converting enzyme
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Conformationally restricted inhibitors of angiotensin converting enzyme: synthesis and computations.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 6.65 | 8.92 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL577 | ENALAPRILAT ANHYDROUS | 4.0 | 1 | 8.92 |
| CHEMBL414828 | — | — | 1 | 4.38 |
| CHEMBL314707 | — | — | 1 | - |
| CHEMBL84966 | — | — | 1 | - |
| CHEMBL316374 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL577 | ENALAPRILAT ANHYDROUS | IC50 | = | 1.2 | nM | 8.92 |
| CHEMBL414828 | — | IC50 | = | 42000.0 | nM | 4.38 |
| CHEMBL314707 | — | IC50 | = | 1700000.0 | nM | - |
| CHEMBL84966 | — | IC50 | = | 440000.0 | nM | - |
| CHEMBL316374 | — | IC50 | = | 480000.0 | nM | - |