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Assay Detail

CHEMBL644711

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Binding
Compound was evaluated for the inhibition of Angiotensin I converting enzyme
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Angiotensin-converting enzyme (CHEMBL1808)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Conformational analysis and active site modelling of angiotensin-converting enzyme inhibitors.
Andrews PR, Carson JM, Caselli A, Spark MJ, Woods R.
J Med Chem (1985) 28 : 393 -399
PubMed 2983076 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 2 9.08 9.30

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL309601 1 9.30
CHEMBL1161022 1 8.85

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL309601 Ki = 0.5 nM 9.30
CHEMBL1161022 Ki = 1.4 nM 8.85