Assay Detail
Binding
CHEMBL644770
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Inhibition of [3H]5'-(N-ethylcarbamoyl)-adenosine binding to adenosine A2 receptor in rat striatal membranes with 50 nM cyclopentyladenosine
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Subcellular | Membrane |
| Confidence | 5 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Publication
8-(Dicyclopropylmethyl)-1,3-dipropylxanthine: a potent and selective adenosine A1 antagonist with renal protective and diuretic activities.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 5.66 | 5.66 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL342782 | — | — | 1 | 5.66 |
| CHEMBL423016 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL342782 | — | Ki | = | 2200.0 | nM | 5.66 |
| CHEMBL423016 | — | Ki | > | 100000.0 | nM | - |