Assay Detail
Binding
CHEMBL644947
Review assay metadata, readout intent, target linkage, and publication context from the same page.
The concentration required to inhibit 3[H]prazosin binding to Alpha-1 adrenergic receptor in rat brain membranes was measured (in vitro)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Tissue | Brain |
| Subcellular | Brain membranes |
| Confidence | 4 — Cell-line / Tissue |
| Curated By | Autocuration |
Publication
Naphthosultam derivatives: a new class of potent and selective 5-HT2 antagonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 7.96 | 7.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL82826 | — | — | 1 | 7.96 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL82826 | — | IC50 | = | 11.0 | nM | 7.96 |