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Assay Detail

CHEMBL645107

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity for human alpha-2B adrenoceptor from cultured Y-1 cells using [3H]rauwolscine
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Cell Type Y-1
Confidence 9 — Direct single protein target
Curated By Expert

Target

Alpha-2B adrenergic receptor (CHEMBL1942)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Pharmacological evaluation of UK-14,304 analogs at cloned human adrenergic receptors
Jeon YT, Luo C, Forray C, Vaysse PJ, Branchek TA, Gluchowski C
Bioorg Med Chem Lett (1995) 5 : 2255 -2258
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 7.37 7.37

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL70676 1 7.37

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL70676 Ki = 42.66 nM 7.37