Assay Detail
Binding
CHEMBL645391
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity towards Alpha-1 adrenergic receptor was evaluated
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 5 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Publication
Azepinoindole derivatives with high affinity for brain dopamine and serotonin receptors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 7.94 | 8.33 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL173315 | — | — | 1 | 8.33 |
| CHEMBL176476 | — | — | 1 | 7.54 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL173315 | — | Ki | = | 4.7 | nM | 8.33 |
| CHEMBL176476 | — | Ki | = | 29.0 | nM | 7.54 |