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Assay Detail

CHEMBL645552

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Compound was evaluated for binding activity against [3H]-WB- 4101 as radioligand for alpha-1 adrenergic receptor
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 4 — Cell-line / Tissue
Curated By Autocuration

Target

Adrenergic receptor alpha-1 (CHEMBL1907610)
Type PROTEIN FAMILY
Organism Rattus norvegicus

Publication

In vitro labeling of serotonin-S2 receptors: synthesis and binding characteristics of [3H]-7-aminoketanserin.
Wouters W, Janssen CG, Van Dun J, Thijssen JB, Laduron PM.
J Med Chem (1986) 29 : 1663 -1668
PubMed 3746815 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 8.26 8.26

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL46683 1 8.26

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL46683 Ki = 5.49 nM 8.26