Assay Detail
Binding
CHEMBL645581
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Compound was tested for binding affinity towards arginyl aminopeptidase
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
alpha-Keto amide inhibitors of aminopeptidases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 8 | 5.54 | 6.77 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL140459 | — | — | 1 | 6.77 |
| CHEMBL143589 | — | — | 1 | 5.82 |
| CHEMBL140846 | — | — | 1 | 5.50 |
| CHEMBL140779 | — | — | 1 | 5.19 |
| CHEMBL309130 | — | — | 1 | 4.41 |
| CHEMBL341941 | — | — | 1 | - |
| CHEMBL142010 | — | — | 1 | - |
| CHEMBL342867 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL140459 | — | Ki | = | 170.0 | nM | 6.77 |
| CHEMBL143589 | — | Ki | = | 1500.0 | nM | 5.82 |
| CHEMBL140846 | — | Ki | = | 3200.0 | nM | 5.50 |
| CHEMBL140779 | — | Ki | = | 6500.0 | nM | 5.19 |
| CHEMBL309130 | — | Ki | = | 39000.0 | nM | 4.41 |
| CHEMBL341941 | — | Ki | = | 130000.0 | nM | - |
| CHEMBL142010 | — | Ki | > | 300000.0 | nM | - |
| CHEMBL342867 | — | Ki | > | 1000000.0 | nM | - |