Assay Detail
Binding
CHEMBL646119
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Compound was tested for its ability to displace [3H]WB-4101 form alpha-1 adrenergic receptor site in guinea pig cerebral cortical membranes.
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Cavia porcellus |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Synthesis and adrenergic activity of ring-fluorinated phenylephrines.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 5.53 | 5.89 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL61372 | — | — | 1 | 5.89 |
| CHEMBL1215 | PHENYLEPHRINE | 4.0 | 1 | 5.60 |
| CHEMBL62072 | — | — | 1 | 5.43 |
| CHEMBL302451 | — | — | 1 | 5.18 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL61372 | — | Ki | = | 1300.0 | nM | 5.89 |
| CHEMBL1215 | PHENYLEPHRINE | Ki | = | 2500.0 | nM | 5.60 |
| CHEMBL62072 | — | Ki | = | 3700.0 | nM | 5.43 |
| CHEMBL302451 | — | Ki | = | 6600.0 | nM | 5.18 |