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Assay Detail

CHEMBL646136

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity towards Adenosine deaminase
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Adenosine deaminase (CHEMBL1910)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Theoretical study of inhibition of adenosine deaminase by (8R)-coformycin and (8R)-deoxycoformycin.
Marrone TJ, Straatsma TP, Briggs JM, Wilson DK, Quiocho FA, McCammon JA.
J Med Chem (1996) 39 : 277 -284
PubMed 8568817 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 2 11.00 11.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL604966 CONFORMYCIN 1 11.00
CHEMBL2112110 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL604966 CONFORMYCIN Ki = 0.01 nM 11.00
CHEMBL2112110 Ki = 0.0025 nM -