Assay Detail
Binding
CHEMBL646138
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Inhibition constant (Ki) against Human erythrocyte adenosine deaminase
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Adenosine deaminase inhibitors. Synthesis and biological activity of deaza analogues of erythro-9-(2-hydroxy-3-nonyl)adenine.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 5 | 7.08 | 8.37 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL50378 | EHNA | — | 1 | 8.37 |
| CHEMBL18496 | — | — | 1 | 8.20 |
| CHEMBL18838 | — | — | 1 | 6.92 |
| CHEMBL17822 | — | — | 1 | 4.82 |
| CHEMBL18659 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL50378 | EHNA | Ki | = | 4.3 | nM | 8.37 |
| CHEMBL18496 | — | Ki | = | 6.3 | nM | 8.20 |
| CHEMBL18838 | — | Ki | = | 120.0 | nM | 6.92 |
| CHEMBL17822 | — | Ki | = | 15000.0 | nM | 4.82 |
| CHEMBL18659 | — | Ki | = | 180000.0 | nM | - |