Assay Detail
Binding
CHEMBL646139
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Inhibition constant against human adenosine deaminase was determined
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Structure-based de novo design of non-nucleoside adenosine deaminase inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 7 | 7.10 | 10.48 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1580 | PENTOSTATIN | 4.0 | 1 | 10.48 |
| CHEMBL50378 | EHNA | — | 1 | 8.43 |
| CHEMBL13696 | FR-221647 | — | 1 | 5.23 |
| CHEMBL14106 | — | — | 1 | 4.27 |
| CHEMBL13697 | — | — | 1 | - |
| CHEMBL274814 | — | — | 1 | - |
| CHEMBL274888 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1580 | PENTOSTATIN | Ki | = | 0.033 | nM | 10.48 |
| CHEMBL50378 | EHNA | Ki | = | 3.7 | nM | 8.43 |
| CHEMBL13696 | FR-221647 | Ki | = | 5900.0 | nM | 5.23 |
| CHEMBL14106 | — | Ki | = | 54000.0 | nM | 4.27 |
| CHEMBL13697 | — | Ki | > | 100000.0 | nM | - |
| CHEMBL274814 | — | Ki | > | 100000.0 | nM | - |
| CHEMBL274888 | — | Ki | > | 100000.0 | nM | - |