Assay Detail
Functional
CHEMBL646232
Review assay metadata, readout intent, target linkage, and publication context from the same page.
In vitro functional activity at Alpha-1B adrenergic receptor in rat spleen
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Tissue | Spleen |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Two novel and potent 3-[(o-methoxyphenyl)piperazinylethyl]-5-phenylthien.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 3 | 8.27 | 8.76 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL13856 | A-123189 | — | 1 | 8.76 |
| CHEMBL268758 | A-119637 | — | 1 | 8.69 |
| CHEMBL13647 | BMY-7378 | — | 1 | 7.37 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL13856 | A-123189 | Kd | = | 1.738 | nM | 8.76 |
| CHEMBL268758 | A-119637 | Kd | = | 2.042 | nM | 8.69 |
| CHEMBL13647 | BMY-7378 | Kd | = | 42.66 | nM | 7.37 |