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Assay Detail

CHEMBL646298

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Functional
Alpha-1 adrenergic receptor antagonistic activity on the rat aorta determined by Schild plot.
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Tissue Aorta
Confidence 4 — Cell-line / Tissue
Curated By Autocuration

Target

Adrenergic receptor alpha-1 (CHEMBL1907610)
Type PROTEIN FAMILY
Organism Rattus norvegicus

Publication

Iodoaminopotentidine and related compounds: a new class of ligands with high affinity and selectivity for the histamine H2 receptor.
Hirschfeld J, Buschauer A, Elz S, Schunack W, Ruat M, Traiffort E, Schwartz JC.
J Med Chem (1992) 35 : 2231 -2238
PubMed 1613748 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 1 5.59 5.59

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL72193 1 5.59

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL72193 Kd = 2570.4 nM 5.59