Assay Detail
Binding
CHEMBL646323
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Tested for its ability to inhibit rabbit liver aldehyde oxidase catalyzed oxidation of N-methyl-nicotinamide (NMN)
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Oryctolagus cuniculus |
| Confidence | 8 — Homologous single protein target |
| Curated By | Intermediate |
Publication
Cyclophosphamide potentiation and aldehyde oxidase inhibition by phosphorylated aldehydes and acetals.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 8 | 4.26 | 4.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL102970 | PYRIDOXAL | 3.0 | 1 | 4.52 |
| CHEMBL103375 | — | — | 1 | 4.00 |
| CHEMBL318547 | — | — | 1 | - |
| CHEMBL318466 | — | — | 1 | - |
| CHEMBL105079 | — | — | 1 | - |
| CHEMBL103253 | — | — | 1 | - |
| CHEMBL316980 | — | — | 1 | - |
| CHEMBL102691 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL102970 | PYRIDOXAL | Ki | = | 30000.0 | nM | 4.52 |
| CHEMBL103375 | — | Ki | = | 100000.0 | nM | 4.00 |
| CHEMBL318547 | — | Ki | = | 400000.0 | nM | - |
| CHEMBL318466 | — | Ki | = | 300000.0 | nM | - |
| CHEMBL105079 | — | Ki | = | 1500000.0 | nM | - |
| CHEMBL103253 | — | Ki | = | 300000.0 | nM | - |
| CHEMBL316980 | — | Ki | = | 200000.0 | nM | - |
| CHEMBL102691 | — | Ki | = | 200000.0 | nM | - |