Assay Detail
Binding
CHEMBL646361
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Inhibitory affinity for Adenosine A2 receptor using [3H]N-ethyladenosine-5'-uronamide
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 5 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Publication
Electrophilic derivatives of purines as irreversible inhibitors of A1 adenosine receptors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 6.52 | 6.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL604357 | — | — | 1 | 6.70 |
| CHEMBL275232 | — | — | 1 | 6.33 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL604357 | — | Ki | = | 202.0 | nM | 6.70 |
| CHEMBL275232 | — | Ki | = | 472.0 | nM | 6.33 |