Assay Detail
Binding
CHEMBL646367
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Affinity towards adenosine A2 receptor
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 5 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Publication
An explanation of the substituent effect of 1,3,8-trisubstituted xanthines on adenosine A1/A2 affinity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 6.72 | 7.03 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL18887 | — | — | 1 | 7.03 |
| CHEMBL158507 | — | — | 1 | 6.94 |
| CHEMBL62350 | 8-PHENYL THEOPHYLLINE | — | 1 | 6.19 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL18887 | — | Ki | = | 93.0 | nM | 7.03 |
| CHEMBL158507 | — | Ki | = | 116.0 | nM | 6.94 |
| CHEMBL62350 | 8-PHENYL THEOPHYLLINE | Ki | = | 644.0 | nM | 6.19 |