Assay Detail
Binding
CHEMBL646471
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Compound was evaluated for its inhibitory potency against purified membrane bound rat brain aminopeptidase
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Analgesic dipeptide derivatives. 7. 3,7-Diamino-2-hydroxyheptanoic acid (DAHHA) containing dipeptide analogues of the analgesic compound H-Lys-Trp(Nps)-OMe.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.35 | 7.62 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL354438 | — | — | 1 | 7.62 |
| CHEMBL171497 | — | — | 1 | 6.48 |
| CHEMBL170314 | — | — | 1 | 4.96 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL354438 | — | IC50 | = | 24.0 | nM | 7.62 |
| CHEMBL171497 | — | IC50 | = | 330.0 | nM | 6.48 |
| CHEMBL170314 | — | IC50 | = | 10900.0 | nM | 4.96 |