Assay Detail
Binding
CHEMBL646473
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Compound was tested for binding affinity towards cytosolic aminopeptidase
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
alpha-Keto amide inhibitors of aminopeptidases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 6 | 5.56 | 6.29 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL309130 | — | — | 1 | 6.29 |
| CHEMBL143589 | — | — | 1 | 6.00 |
| CHEMBL140846 | — | — | 1 | 5.72 |
| CHEMBL140459 | — | — | 1 | 4.24 |
| CHEMBL341941 | — | — | 1 | - |
| CHEMBL140779 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL309130 | — | Ki | = | 510.0 | nM | 6.29 |
| CHEMBL143589 | — | Ki | = | 1000.0 | nM | 6.00 |
| CHEMBL140846 | — | Ki | = | 1900.0 | nM | 5.72 |
| CHEMBL140459 | — | Ki | = | 57000.0 | nM | 4.24 |
| CHEMBL341941 | — | Ki | = | 1100000.0 | nM | - |
| CHEMBL140779 | — | Ki | > | 15000.0 | nM | - |