Assay Detail
Binding
CHEMBL646576
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of saturable binding of [3H]prazosin to alpha-1 adrenergic receptor in rat cerebral cortical membranes.
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Subcellular | Membrane |
| Confidence | 4 — Cell-line / Tissue |
| Curated By | Autocuration |
Publication
Indoline analogues of idazoxan: potent alpha 2-antagonists and alpha 1-agonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 1 | 7.76 | 7.76 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL289153 | — | — | 1 | 7.76 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL289153 | — | Ki | = | 17.5 | nM | 7.76 |