Assay Detail
Binding
CHEMBL646884
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Compound was tested for inhibitory activity against alpha-glucosidase.
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Saccharomyces cerevisiae |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Synthesis of potent -D-glucocerebrosidase inhibitors: N-alkyl--valienamines
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 4.27 | 4.77 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL422734 | — | — | 1 | 4.77 |
| CHEMBL354193 | — | — | 1 | 4.30 |
| CHEMBL1230806 | VALIENAMINE | — | 1 | 4.00 |
| CHEMBL1744444 | (BETA)-VALIENAMINE | — | 1 | 4.00 |
| CHEMBL367666 | — | — | 1 | - |
| CHEMBL426933 | — | — | 1 | - |
| CHEMBL174067 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL422734 | — | IC50 | = | 17000.0 | nM | 4.77 |
| CHEMBL354193 | — | IC50 | = | 50000.0 | nM | 4.30 |
| CHEMBL1230806 | VALIENAMINE | IC50 | = | 100000.0 | nM | 4.00 |
| CHEMBL1744444 | (BETA)-VALIENAMINE | IC50 | = | 100000.0 | nM | 4.00 |
| CHEMBL367666 | — | IC50 | < | 100000.0 | nM | - |
| CHEMBL426933 | — | IC50 | < | 100000.0 | nM | - |
| CHEMBL174067 | — | IC50 | < | 100000.0 | nM | - |