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Quick search ChEMBL 36
Compound Detail

CHEMBL1744444

(BETA)-VALIENAMINE
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C[C@]12CCC(=O)C[C@@H]1CC[C@@H]1[C@@H]2CC[C@]2(C)[C@@H](O)CC[C@@H]12.C[C@]12CC[C@H]3[C@@H](CCC4CC(=O)CC[C@@]43C)[C@@H]1CC[C@@H]2O

Basic Information

ChEMBL ID CHEMBL1744444
Name (BETA)-VALIENAMINE
Phase Preclinical
Structure Type MOL
InChI Key BRJXOAXKWKKGJK-NHDCPNEFSA-N
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names

Molecular Properties

580.9
MW (Da)

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C38H60O4
MW 580.89

Activity Summary

IC50 1 meas. best 4.0

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Maltase-glucoamylase
CHEMBL2074
IC50 4.0 4.0 100000.0 1

Activity Data Samples

Top measurements by pChEMBL value

Target Type Rel. Value Units pChEMBL Assay PubMed
Maltase-glucoamylase IC50 = 100000.0 nM 4.0 Compound was tested for inhibitory activity against alpha-glucosidase. -

Literature References

PubMed DOI Target Context # Activities
- 10.1016/0960-894X(96)00146-1 Lysosomal acid glucosylceramidase 1
- 10.1016/0960-894X(96)00146-1 Unchecked 1
- 10.1016/0960-894X(96)00146-1 Maltase-glucoamylase 1

Data from ChEMBL 36 via Core Engine