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Assay Detail

CHEMBL647040

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Compound is evaluated for receptor binding affinity using 100 nM concentration on rat cerebral cortical membranes
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 4 — Cell-line / Tissue
Curated By Autocuration

Target

Adrenergic receptor alpha-1 (CHEMBL1907610)
Type PROTEIN FAMILY
Organism Rattus norvegicus

Publication

Alkylating prazosin analogue: irreversible label for alpha 1-adrenoceptors.
Pitha J, Szabo L, Szurmai Z, Buchowiecki W, Kusiak JW.
J Med Chem (1989) 32 : 96 -100
PubMed 2535878 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 1 9.38 9.38

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL268768 1 9.38

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL268768 Kd = 0.412 nM 9.38