Assay Detail
Functional
CHEMBL647357
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Agonistic activity against alpha alpha-2 adrenergic receptor in isolated, field -simulated vas deferens from rats
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Confidence | 4 — Cell-line / Tissue |
| Curated By | Autocuration |
Publication
alpha-Adrenergic activities of some substituted 2-(aminomethyl)imidazolines.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 7 | 7.13 | 7.13 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL51479 | — | — | 1 | 7.13 |
| CHEMBL300053 | — | — | 1 | - |
| CHEMBL597 | PHENTOLAMINE | 4.0 | 1 | - |
| CHEMBL49953 | — | — | 1 | - |
| CHEMBL541208 | — | — | 1 | - |
| CHEMBL300628 | — | — | 1 | - |
| CHEMBL51131 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL51479 | — | EC50 | = | 74.0 | nM | 7.13 |
| CHEMBL300053 | — | EC50 | > | 2000.0 | nM | - |
| CHEMBL597 | PHENTOLAMINE | EC50 | > | 1000.0 | nM | - |
| CHEMBL49953 | — | EC50 | > | 10000.0 | nM | - |
| CHEMBL541208 | — | EC50 | > | 10000.0 | nM | - |
| CHEMBL300628 | — | EC50 | > | 2000.0 | nM | - |
| CHEMBL51131 | — | EC50 | > | 10000.0 | nM | - |