Assay Detail
Functional
CHEMBL647416
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Agonistic potency at beta adrenergic receptor for the stimulation of accumulation of cyclic AMP in cultured C6 glioma cells
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Cell Type | C6 |
| Confidence | 4 — Cell-line / Tissue |
| Curated By | Autocuration |
Publication
Syntheses and adrenergic activities of ring-fluorinated epinephrines.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 7.02 | 7.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL43711 | — | — | 1 | 7.40 |
| CHEMBL679 | EPINEPHRINE | 4.0 | 1 | 6.64 |
| CHEMBL42359 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL43711 | — | EC50 | = | 40.0 | nM | 7.40 |
| CHEMBL679 | EPINEPHRINE | EC50 | = | 230.0 | nM | 6.64 |
| CHEMBL42359 | — | EC50 | > | 1500.0 | nM | - |