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Assay Detail

CHEMBL647654

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibitory activity against sweet almond Beta-glucosidase
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Prunus dulcis
Confidence 8 — Homologous single protein target
Curated By Expert

Target

Beta-glucosidase (CHEMBL4192)
Type SINGLE PROTEIN
Organism Prunus avium

Publication

The Interaction of Anhydroalditols with Sweet-Almond -glucosidase and Escherichia coli -galactosidase: implications for the design of potent glycosidase inhibitors
Field RA, Haines AH, Chrystal EJ
Bioorg Med Chem Lett (1991) 1 : 667 -672
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 2 5.99 6.96

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL157924 1 6.96
CHEMBL307429 DUVOGLUSTAT 2.0 1 5.02

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL157924 Ki = 110.0 nM 6.96
CHEMBL307429 DUVOGLUSTAT Ki = 9500.0 nM 5.02