Assay Detail
Binding
CHEMBL647747
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibitory activity against Androgen receptor
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Mus musculus |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Novel 6-aryl-1,4-dihydrobenzo[d]oxazine-2-thiones as potent, selective, and orally active nonsteroidal progesterone receptor agonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.93 | 7.43 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL103 | PROGESTERONE | 4.0 | 1 | 7.43 |
| CHEMBL282650 | — | — | 1 | 6.42 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL103 | PROGESTERONE | IC50 | = | 37.0 | nM | 7.43 |
| CHEMBL282650 | — | IC50 | = | 379.0 | nM | 6.42 |