Assay Detail
Binding
CHEMBL647887
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of binding of [125I]- Sar,Ileu-angiotensin to Angiotensin II receptor, type 1 in the radioligand binding assay using rat liver membrane preparations
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Tissue | Liver |
| Subcellular | Membrane |
| Confidence | 4 — Cell-line / Tissue |
| Curated By | Autocuration |
Target
Angiotensin II receptor (AT-1) type-1 (CHEMBL2094250) ↗| Type | PROTEIN FAMILY |
| Organism | Rattus norvegicus |
Publication
Cycloheptimidazole based angiotensin II receptor antagonists. 4,5,6,7-tetrahydro-8-carboxymethylidene cycloheptimidazoles
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 8.26 | 8.26 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL43591 | — | — | 1 | 8.26 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL43591 | — | IC50 | = | 5.45 | nM | 8.26 |