Assay Detail
Binding
CHEMBL647939
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Compound was evaluated for the inhibitory activity against aminopeptidase M
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Sus scrofa |
| Confidence | 9 — Direct single protein target |
| Curated By | Intermediate |
Publication
Inhibition of aminopeptidases by amastatin and bestatin derivatives. Effect of inhibitor structure on slow-binding processes.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.74 | 5.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL28650 | AMASTATIN | — | 1 | 5.96 |
| CHEMBL538595 | BESTATIN HYDROCHLORIDE | — | 1 | 5.52 |
| CHEMBL2370764 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL28650 | AMASTATIN | IC50 | = | 1100.0 | nM | 5.96 |
| CHEMBL538595 | BESTATIN HYDROCHLORIDE | IC50 | = | 3030.0 | nM | 5.52 |
| CHEMBL2370764 | — | IC50 | > | 500000.0 | nM | - |