Assay Detail
Binding
CHEMBL648313
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Binding affinity towards adenosine A1 receptor in rat brain membrane(KD)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Tissue | Brain |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Photoaffinity labeling adenosine A1 receptors with an antagonist 125I-labeled aryl azide derivative of 8-phenylxanthine.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 3 | 9.04 | 9.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL355370 | — | — | 1 | 9.10 |
| CHEMBL161933 | — | — | 1 | 9.10 |
| CHEMBL164623 | — | — | 1 | 8.92 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL355370 | — | Kd | = | 0.8 | nM | 9.10 |
| CHEMBL161933 | — | Kd | = | 0.8 | nM | 9.10 |
| CHEMBL164623 | — | Kd | = | 1.2 | nM | 8.92 |