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Assay Detail

CHEMBL648319

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
In vitro beta adrenergic receptor blocking in guinea pig trachea
2
Total Activities
2
Compounds Tested
2
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Cavia porcellus
Tissue Trachea
Confidence 4 — Cell-line / Tissue
Curated By Autocuration

Target

Adrenergic receptor beta (CHEMBL2094118)
Type PROTEIN FAMILY
Organism Homo sapiens

Publication

[(Arylcarbonyl)oxy]propanolamines. 1. Novel beta-blockers with ultrashort duration of action.
Kam ST, Matier WL, Mai KX, Barcelon-Yang C, Borgman RJ, O'Donnell JP, Stampfli HF, Sum CY, Anderson WG, Gorczynski RJ.
J Med Chem (1984) 27 : 1007 -1016
PubMed 6146718 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 1 8.20 8.20
pA2 1 - -

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL6935 1 8.20
CHEMBL7509 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL6935 Kd = 6.31 nM 8.20
CHEMBL7509 pA2 - -