Assay Detail
Binding
CHEMBL648326
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Binding affinity against human androgen receptor (hAR) in competitive binding assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Homology modeling using multiple molecular dynamics simulations and docking studies of the human androgen receptor ligand binding domain bound to testosterone and nonsteroidal ligands.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 8.13 | 9.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL296323 | — | — | 1 | 9.52 |
| CHEMBL48159 | — | — | 1 | 7.78 |
| CHEMBL49615 | — | — | 1 | 7.09 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL296323 | — | Ki | = | 0.3 | nM | 9.52 |
| CHEMBL48159 | — | Ki | = | 16.5 | nM | 7.78 |
| CHEMBL49615 | — | Ki | = | 80.9 | nM | 7.09 |