Assay Detail
Binding
CHEMBL648428
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Binding affinity towards Alpha-2 adrenergic receptor was measured through displacement of [3H]-RX-821002
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 4 — Cell-line / Tissue |
| Curated By | Autocuration |
Publication
1-Benzyloxy-4,5-dihydro-1H-imidazol-2-yl-amines, a novel class of NR1/2B subtype selective NMDA receptor antagonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 4.76 | 5.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL108043 | — | — | 1 | 5.00 |
| CHEMBL107193 | — | — | 1 | 4.52 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL108043 | — | Ki | = | 10000.0 | nM | 5.00 |
| CHEMBL107193 | — | Ki | = | 30000.0 | nM | 4.52 |