Assay Detail
Binding
CHEMBL648497
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Binding radioligand
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Caenorhabditis elegans |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Syntheses and biological activities of 13-substituted avermectin aglycons.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 5 | 9.68 | 10.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1630577 | ABAMECTIN COMPONENT B1A | -1.0 | 1 | 10.00 |
| CHEMBL6067487 | IVERMECTIN | 4.0 | 1 | 9.52 |
| CHEMBL125433 | — | — | 1 | 9.52 |
| CHEMBL434439 | — | — | 1 | - |
| CHEMBL339503 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1630577 | ABAMECTIN COMPONENT B1A | Ki | = | 0.1 | nM | 10.00 |
| CHEMBL6067487 | IVERMECTIN | Ki | = | 0.3 | nM | 9.52 |
| CHEMBL125433 | — | Ki | = | 0.3 | nM | 9.52 |
| CHEMBL434439 | — | Ki | > | 100.0 | nM | - |
| CHEMBL339503 | — | Ki | > | 100.0 | nM | - |