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Assay Detail

CHEMBL648510

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Effective potency in transcriptional activation assay in CV-1 cells expressing Retinoid X receptor RXR gamma
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Mus musculus
Cell Type CV-1
Confidence 9 — Direct single protein target
Curated By Expert

Target

Retinoic acid receptor RXR-gamma (CHEMBL4402)
Type SINGLE PROTEIN
Organism Mus musculus

Publication

Synthesis and structure-activity relationships of potent retinoid X receptor ligands
Farmer LJ, Jeong S, Kallel E, Canan Koch SS, Croston GE, Flatten KS, Heyman RA, Nadzan AM
Bioorg Med Chem Lett (1997) 7 : 2393 -2398
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 6.69 6.69

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL80424 1 6.69

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL80424 EC50 = 204.0 nM 6.69