Assay Detail
Binding
CHEMBL648724
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Binding affinity for rat alpha-2 adrenergic receptor from crude P2 membranes
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 5 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Publication
Binding of an imidazopyridoindole at imidazoline I2 receptors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 5.43 | 6.15 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL269236 | TRYPTOLINE | — | 1 | 6.15 |
| CHEMBL404505 | — | — | 1 | 5.40 |
| CHEMBL275970 | TRACIZOLINE | — | 1 | 5.13 |
| CHEMBL6310 | — | — | 1 | 5.05 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL269236 | TRYPTOLINE | Ki | = | 710.0 | nM | 6.15 |
| CHEMBL404505 | — | Ki | = | 4000.0 | nM | 5.40 |
| CHEMBL275970 | TRACIZOLINE | Ki | = | 7413.0 | nM | 5.13 |
| CHEMBL6310 | — | Ki | = | 8840.0 | nM | 5.05 |