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Assay Detail

CHEMBL648949

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Binding
Inhibition of Angiotensin I converting enzyme (ACE)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Angiotensin-converting enzyme (CHEMBL2625)
Type SINGLE PROTEIN
Organism Rattus norvegicus

Publication

Toward an optimal joint recognition of the S1' subsites of endothelin converting enzyme-1 (ECE-1), angiotensin converting enzyme (ACE), and neutral endopeptidase (NEP).
Inguimbert N, Coric P, Poras H, Meudal H, Teffot F, Fournié-Zaluski MC, Roques BP.
J Med Chem (2002) 45 : 1477 -1486
PubMed 11906289 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 8.60 8.60

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL43370 1 8.60

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL43370 IC50 = 2.5 nM 8.60