Angiotensin-converting enzyme · SINGLE PROTEIN · Rattus norvegicus
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As of 2026-09-13Protein identity stays anchored to UniProt P47820. Use UniProt P47820 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P47820 as the stable identity anchor, then attach disease evidence before program review.
Angiotensin-converting enzyme
Review this target as Angiotensin-converting enzyme, mapped to UniProt P47820. Sequence length is 1313 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Angiotensin-converting enzyme as ChEMBL target CHEMBL2625, mapped to UniProt P47820. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Angiotensin-converting enzyme |
| Target Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
| UniProt | P47820 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Angiotensin-converting enzyme |
| UniProt Accession | P47820 |
| Component Type | Protein |
| Sequence Length | 1313 aa |
Angiotensin-converting enzyme
Review this target as Angiotensin-converting enzyme, mapped to UniProt P47820. Sequence length is 1313 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL20341 | 9.59 | IC50 | 0.26 | Preclinical |
| CHEMBL287896 | 9.52 | IC50 | 0.3 | Preclinical |
| CHEMBL410980 | 9.46 | IC50 | 0.35 | Preclinical |
| CHEMBL19951 | 9.4 | IC50 | 0.4 | Preclinical |
| CHEMBL88278 | 9.38 | IC50 | 0.42 | Preclinical |
| CHEMBL86884 | 9.34 | IC50 | 0.46 | Preclinical |
| CHEMBL329125 | 9.3 | IC50 | 0.5 | Preclinical |
| CHEMBL342372 | 9.29 | IC50 | 0.51 | Clinical |
| CHEMBL419499 | 9.26 | IC50 | 0.55 | Preclinical |
| CHEMBL20182 | 9.24 | IC50 | 0.58 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| organism-based format | 123 | 6 | 7.2 |
| single protein format | 48 | 304 | 7.2 |
| cell-free format | 5 | 14 | 6.2 |
| assay format | 3 | 16 | 6.5 |
| tissue-based format | 1 | 25 | 7.3 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| organism-based format | 34 | 0 | — |
| assay format | 6 | 1 | 8.1 |