Compound Detail
CHEMBL342372
UTIBAPRILAT 🧪 Phase II
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
🧪 Phase II
C[C@H](N[C@@H](CCc1ccccc1)C(=O)O)C(=O)N1N=C(C(C)(C)C)S[C@H]1C(=O)O
Basic Information
| ChEMBL ID | CHEMBL342372 |
| Name | UTIBAPRILAT |
| Phase | Phase II |
| Structure Type | MOL |
| InChI Key | APWZQGVRPRWXQK-NOLJZWGESA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
3
Publications
2
Known Names
Molecular Properties
421.5
MW (Da)
2.40
ALogP
6
HBA
3
HBD
119.3
PSA (Ų)
0.59
QED
0
Ro5 Violations
8
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Chirality | Single Enantiomer |
Activity Summary
IC50 1 meas. best 9.29
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Angiotensin-converting enzyme CHEMBL2625 | IC50 | 9.29 | 9.29 | 0.5 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Angiotensin-converting enzyme | IC50 | = | 0.51 | nM | 9.29 | Compound was tested for inhibitory activity against angiotensin I converting enz... | 1992145 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 1992145 | 10.1021/jm00105a066 | No relevant target | 3 |
| 1992145 | 10.1021/jm00105a066 | Angiotensin-converting enzyme | 1 |
| 1992145 | 10.1021/jm00105a066 | NON-PROTEIN TARGET | 1 |
Data from ChEMBL 36 via Core Engine