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Assay Detail

CHEMBL649182

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity against Alpha-1 adrenergic receptor
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 4 — Cell-line / Tissue
Curated By Autocuration

Target

Adrenergic receptor alpha-1 (CHEMBL2094251)
Type PROTEIN FAMILY
Organism Homo sapiens

Publication

7-Methyl-6,7,8,9,14,15-hexahydro-5H-benz[d]indolo[2,3-g]azecine: a new heterocyclic system and a new lead compound for dopamine receptor antagonists.
Witt T, Hock FJ, Lehmann J.
J Med Chem (2000) 43 : 2079 -2081
PubMed 10821720 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 7.96 7.96

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL441618 1 7.96

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL441618 Ki = 11.0 nM 7.96