Assay Detail
Binding
CHEMBL649280
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Binding affinity was measured at the Alpha-1 adrenergic receptor using [3H]prazosin as radioligand in rat brain cortex membrane.
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Tissue | Brain |
| Confidence | 4 — Cell-line / Tissue |
| Curated By | Autocuration |
Publication
N-[2-[4-(4-Chlorophenyl)piperazin-1-yl]ethyl]-3-methoxybenzamide: a potent and selective dopamine D4 ligand.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.49 | 6.57 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL93403 | — | — | 1 | 6.57 |
| CHEMBL147483 | — | — | 1 | 6.47 |
| CHEMBL286725 | — | — | 1 | 6.44 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL93403 | — | IC50 | = | 270.0 | nM | 6.57 |
| CHEMBL147483 | — | IC50 | = | 340.0 | nM | 6.47 |
| CHEMBL286725 | — | IC50 | = | 360.0 | nM | 6.44 |