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Assay Detail

CHEMBL649414

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibitory activity against alpha-glucosidase from rat intestinal maltase
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Neutral alpha-glucosidase C (CHEMBL3635)
Type SINGLE PROTEIN
Organism Mus musculus

Publication

Revised structure of a homonojirimycin isomer from Aglaonema treubii: first example of a naturally occurring alpha-homoallonojirimycin.
Martin OR, Compain P, Kizu H, Asano N.
Bioorg Med Chem Lett (1999) 9 : 3171 -3174
PubMed 10560746 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 5.41 6.47

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL501355 1 6.47
CHEMBL327137 1 4.34

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL501355 IC50 = 340.0 nM 6.47
CHEMBL327137 IC50 = 46000.0 nM 4.34