Compound Detail
CHEMBL501355
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Basic Information
| ChEMBL ID | CHEMBL501355 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | CLVUFWXGNIFGNC-OVHBTUCOSA-N |
8
Targets
16
Activities
2
Assay Types
2
PK Parameters
19
Publications
0
Known Names
Molecular Properties
193.2
MW (Da)
-3.61
ALogP
6
HBA
6
HBD
113.2
PSA (Ų)
0.27
QED
1
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 15 meas. best 7.4
EC50 1 meas.
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Maltase-glucoamylase CHEMBL2074 | IC50 | 7.4 | 7.4 | 40.0 | 1 |
| Acidic alpha-glucosidase CHEMBL3513 | IC50 | 7.1 | 6.36 | 80.0 | 6 |
| Unchecked CHEMBL612545 | IC50 | 7.05 | 7.05 | 90.0 | 1 |
| Lysosomal alpha-glucosidase CHEMBL2608 | IC50 | 7.0 | 6.5 | 100.0 | 2 |
| Glycogen debranching enzyme CHEMBL5273 | IC50 | 6.96 | 6.96 | 110.0 | 1 |
| Sucrase-isomaltase, intestinal CHEMBL3114 | IC50 | 6.77 | 6.465 | 170.0 | 2 |
| Neutral alpha-glucosidase C CHEMBL3635 | IC50 | 6.47 | 6.47 | 340.0 | 1 |
| Trehalase CHEMBL3248 | IC50 | 4.47 | 4.47 | 34000.0 | 1 |
Pharmacokinetic Data
| Parameter | Value | Units | Species |
|---|---|---|---|
| AUC | 2994000.0 | ng.hr.mL-1 | Mus musculus |
| AUC | 2682000.0 | ng.hr.mL-1 | Mus musculus |
Activity Data Samples
Top measurements by pChEMBL value
Literature References
Data from ChEMBL 36 via Core Engine